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Abstract Urinary tract infection has been well documented in both normal and high-risk neonates (Maherzi et al, 1978). It may be associated with bacteremia and sepsis, or it may be the first sign of an anatomic abnormality of genitourinary tract. Delay in the treatment of urinary tract infection can lead to renal scarring despite the absence of a significant structural abnormality (Filly et al., 1974). Adherence of bacteria to uroepithelium is the first step in urinary tract infection followed by colonigation, tissue damage and in some cases ultimately invasion and dissemination (Schaffer, 1989). The aim of this work to study the problem of urinary tract infection and the role of bacterial adherence among high risk neonates. This study was conducted on (95) pre-term and full term neonates and firstly they were clinicaly categorized into three main groups:- group (I) from (28-32 weeks), group (II) from (33-37 weeks) and group (III) from (38-42 weeks). After laboratory investigations each group was further subdivied into three subgroups as following:- Subgroup (a); symptomatic with sepsis . ., ., Subgroup (b); symptomatic without sepsis. Subgroup (c); Asymptomatic without sepsis. 65 |