الفهرس | Only 14 pages are availabe for public view |
Abstract Between January 1982 and December 1994 five adult patients with bladder sarcoma were treated at our center. There were 4 males and one female with mean age 34 years. Four patients had low grade leiomyosarcoma and one had metastatic carcinosarcoma. Three patients underwent radical cystectomy and urinary diversion. They are all alive free of disease 3,6 and 9 years after surgery. One patient, was subjected to subtotal cystectomy and ileocystoplasty. This patient died of local recurrence 4 years after surgery. The patient with metastatic carcinosarcoma was treatf3d by palliative endoscopic resection and systemic doxorubicin. Unfortunately drug toxicity occured followed by progression and death one year after treatment. .. No clear cut conclusion could be drawn with this limited number of cases. However, with rare tumors some observations are noteworthy. Radical surgery- is the best treatment for adult bladder sarcoma and carry the best survival. Present day chemotherapeutic regemins are ineffective in controlling dissiminated sarcoma. The development of more effective systemic therapy is needed to control metastatic disease. V.2- Pediatric patients with lower urinary tract sarcoma: A total of 25 children with lower urinary tract rhabdomyosarcoma were seen at our center from January 1982 to December 1994. There were 21 males and 4 females. The mean age of the patients was 7.5 years. Urinary outflow obstruction was the main presenting symptom. The primary tumor. location was the bladder in 11 patients and the prostate in 6 patients. Both bladder and prostate were involved in 8 cases. The primary tumor size (Widest diameter) ranged between 3 and 15 cm with a mean of 9 cm. |