الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
The primary goal of the surgical oncologist in the pperative treatment of solid tumors is to perform a complete resection, usually at a microscopic level, this ability is enhanced by a technique known , as the ”Radioimmunoguided Surgery” (RIGS). The evolution of the RIGS system is based on the radioimmunodetection, which was flfst by external imaging ”Immunoscintigraphy,” then intraoperative detection ”Radioimmunoguided Surgery”. The radioimmunodetection exploits the. expression of tumor associated antigens ( T AAs ) found on the s.urface of human adenocarcinomas, which are targeted by radiolabeled monoclonal antibodies. Colorectal cancer is the most frequently studied tumor type by the Radioimmunodetection ( RAID ) because a number of antigens and monoclonal antibodies associated with the tumor are available. The concept of radioimmunodetection was flfSt explored by Pressman using radiolabeled polyclonal antibodies and demonstrated antibody targeting of tumors in animals