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العنوان
Role of endogenous opioids on carbohydrate metabolism in response to physical training in rats /
الناشر
Jehan Abdel Hamid El-Wakil,
المؤلف
El-Wakil, Jehan Abdel Hamid.
هيئة الاعداد
باحث / جيهان عبد الحميد حسن الوكيل
مشرف / سهير عباس حلمى
مشرف / محمد زين العابدين برعى
مناقش / سهير عباس حلمى
مناقش / محمد زين العابدين برعى
الموضوع
Carbohydrate metabolism-- Physical diagnosis.
تاريخ النشر
2000.
عدد الصفحات
157 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2000
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم الفسيولوجيا.
الفهرس
Only 14 pages are availabe for public view

from 176

from 176

Abstract

It is well established that physical training enhances glucose utilization by peripheral tissues particularly the skeletal muscles. Several investigators have reported that level of endogenous opioid peptides is increased in physically trained individuals. This elevated level may participate in the changes observed in carbohydrate metabolism in trained subjects. The present work was conducted to study the effect of physical training on carbohydrate metabolism and to evaluate the role of endogenous opioids on carbohydrate metabolism in response to physical training. Albino rats of both sexes were used in this work. The animals were incubated in the laboratory with free access to water and usual diet. The animals were then divided into 2 main groups: Group I : 40 sedentary rats(untrained group). Group II : 40 physically trained rats for 6 weeks (trained group). Each main group is subdivided into 4 subgroups: Group A : 10 control rats. Group B : 10 rats injected with naloxone (0.5 mg/kg I.P) . Group C : lO rats injected with naloxone and alpha- adrenergic blocker (phentolamine) (0.5 mg/kg I.P) . Group D : 10 rats injected with naloxone and beta- adrenergic blocker (propranolol) ( 1 mg/kg I.P) . The trained group was allowed to swim in a deep glass container five days per week for six weeks, the duration of swimming was gradually increased during the first two weeks untill the exercised rats could swim two hours per day.