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العنوان
Intrafollicular insemination versus intraperitoneal insemination in infertility treatment /
الناشر
Emad Fawky Atwa El-Adawy,
المؤلف
El-Adawy, Emad Fawky Atwa.
هيئة الاعداد
باحث / عماد فوقي عطوة العدوي
مشرف / محمد مصطفي الشافعي
مشرف / لطفي شريف شريف
مشرف / ليلي عبد الحميد البغدادي
مشرف / محمد أحمد إمام
الموضوع
Infertility treatment.
تاريخ النشر
2002.
عدد الصفحات
149 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2002
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم النسا والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

Our study was conducted to evaluate the intrafollicular insemination as a new technique of artificial insemination and to compare its effectiveness with that of intraperitoneal insemination in treatment of unexplained infertility, male factor infertility and cervical factor infertility. The study involved a total of 138 infertile couples belonging to 3 infertility categories; unexplained (n = 52), male factor (n = 46) and cervical factor infertility (n = 40). The patients of each infertility category were divided randomly into two equal subgroups A and B each of which comprised 26 couples with unexplained infertility, 23 couples with male factor infertility and 20 couples with cervical factor infertility. Couples of subgtoup A were treated by ovarian stimulation plus direct intrafollicular insemination while couples of subgroup B were treated by ovarian stimulation plus direct intraperitoneal insemination. The treatment was given every other cycle for one to three cycles. The cycle before and all cycles in between the treatment cycles were served as control cycles during which no treatment was given. Direct intrafollicular insemination was found ro be effective treatment for all the 3 infertility categories involved in this study. The pregnancy rate in unexplained infertility was 15.94% which is significantly higher than the pregnancy rate in the control cycles which was 1.43% (p. value = 0.008). Also, the pregnancy rate in male factor infertility was 17.54% which is significantly higher than that of the control cycles which was 1.72% (P. Value = 0.01). Lastly, the pregnancy rate in cervical factor infertility was 15.38% which is significantly higher than that of the control cycles which was 1.89% (P. value = 0.034). When we compared the pregnancy rates in unexplained infertility, male factor infertility and cervical factor infertility (15.94%, 17.54% and 15.38% respectively) following intrafollicular insemination there was no significant difference in the pregnancy rates between the 3 groups, this means that the technique is nearly equally effective in the treatment of the 3 infertility categories. .r On the other hand, intraperitoneal insemination was found to be effective treatment for unexplained infertility and cervical factor infertility but not male factor infertility. The pregnancy rate in unexplained infertility was 14.7% which is significantly higher than that of the control cycles which is ] .45% (P. value = 0.0 I]). Also, the pregnancy rate in cervical factor infertility was 14.8% which is significantly higher than that of the control cycles which’ is 1.8% (P. value..