الفهرس 
INTRODUCTION& Aim of the workOnly 14 pages are availabe for public view
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Abstract
Introduction: Eczema is an inflammatory skin reaction characterized histologically by spongiosis with varying degrees of acanthosis and superficial perivasculer lymphohistiocytic infiltrate. Manifestations of eczema may include :itching, redness, scaling and clustered papulovesicles . Meanwhile, renal transplant recipients receive immunomodulator drugs in order to avoid rejection of the transplant, however, these drugs affect the immune system by various ways and the major effects include: Immunosuppression, Allergy, Autoimmunity and Immunoactivation. Aim of the work: to evaluate the proportion of eczema among renal transplant recipients on different immunosuppressive protocols and to study some immunological changes related to eczema among those patients. Subjects & Methods: This study was conducted on 86 patients (67 males and 19 females) whom had a renal transplantation operation as recipients. The patient were selected from the outpatient clinic and nephrology department inpatient of the Mansoura University Urology and Nephrology Center during the period between August 2002 to July 2003. The patients ages ranged from 7 to 63 years. Conclusions: We concluded that: Proportion of eczema was decreased to about the half after renal transplantation,Severity of eczema also decreased in the same patient after transplantation, After transplantation incidence of some skin diseases was decreased especially xerosis, pruritis and eczema, while others are increased as acne vulgaris and infections, Patch test has less diagnostic value after renal transplantation, Tacrolimus, CsA, Rapamycin and Steroid in combination decreased the incidence and severity of eczema, No obvious difference between patients on systemic tacrolimus and others not taking tacrolimus regarding protection against eczema and skin side effects, IgE level in serum directly correlate with results of patch test, Tacrolimus and CsA suppressed the level of serum IgE and finally that CsA, Tacrolimus and Rapamycin suppresses immunity by different mechanisms.