الفهرس 
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Abstract
The main objective of pulpotomy procedure in primary teeth is to preserve the tooth till normal exfoliation. The formocresol pulpotomy technique is considered the most universally taught and preferred pulp therapy for primary teeth at the present time. Despite years of apparent successful use as a pulpotomy agent, formocresol has come under attack for the research which have shown formaldehyde to be toxic, mutagenic and carcinogenic. The response to the controversy has been a quest for alternative agent and techniques. Currently, the technique receiving attention is ferric sulfate and tetrandrine as alternative medicaments for pulpotomy. It would be ideal to utilize medicament that lead to healing of the pulp and allow for the continuity of normal pulp physiology at remaining part. The purposes of this study were to evaluate pulpotomy medicaments such as ferric sulfate and tetrandrine in comparison to formocresol clinically, radio graphically and experimentally. The clinical part of this study was carried out on 80 carious primary molar of 40 children. They were selected from Pediatric Dentistry Clinic, Faculty of Dentistry, Mansoura University. Their ages ranged from 37 years. They were divided into two main groups each one 20 child. In every child one molar in one side was treated with ferric sulfate or tetrandrine, while in the other side the counterlateral tooth treated with formocresol and served as control. Children were followed up at 48 hour, 1 month, 6 month, 12 month and 18 month. At each recall appointment the children were examined clinically and radiographically as regard pain, swelling, mobility loss of lamina dura integrity, internal, external and root resorption, interradicular pathosis and periapcial pathosis. 80 molars of 8 puppies were used for the experimental part. They were divided into 2 main groups. In the first group 40 molars were divided equally for ferric sulfate and its formocresol control at the counterlateral side of the same animal. The second group consisted of 40 molars were divided equally for tetrandrine and formocresol. After (1 day 1 week 1 month and 2 months ) the animals were sacrificed and the treated teeth were prepared and evaluated histologically. The evaluation of all materials was based on the ranking of each tooth, using specific criteria. The histological evaluation revealed that normal pulp response and the least hyperemic reaction observed with ferric sulfate, the least inflammatory reaction with tetrandrine. Both materials had better pulp response than formocresol. At the end of the study, clinical evaluation of pulpotomized molars treated by ferric sulfate revealed pain in 2 treated molars while one molar had swelling, 3 molars had mobility in addition to extraction of 1 molar that had pain and swelling. As regards to its formocresol control group 3 molars had pain sign, swelling in 2 molars, mobility of 2 molars and 2 extracted molars that had pain and swelling. In tetrandrine study group, 3 molars showed mobility, one of them had pain and swelling, no extraction was registered. In relation its formocresol control group 3 molars had pain sign, swelling in 2 molars, mobility of 3 molars. One molar was extracted. The radiographic examination confirms the clinical results mentioned above when evaluated regarding internal, external, root resorption, interradicualar pathosis and periapical pathosis.