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Abstract Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy encountered in electrodiagnostic laboratories. It can be defined as impairment of motor and/or sensory function of the median nerve as it traverses through the carpal tunnel. Objectives: The aim of this study was to assess the diagnostic accuracy of MR imaging and electrophysiologic testing in cases with CTS and to evaluate the correlation between the clinical, electrophysiologic and MRI findings of CTS. Methods: Fifty five wrists in thirty two patients with clinically diagnosed CTS were evaluated by thorough clinical assessment, laboratory investigations, MRI on the wrist region and neurophysiological testing including needle electromyography and nerve conduction studies. Results: The diagnostic sensitivity of electrophysiologic testing was 89.1%. The overall sensitivity of MRI for CTS diagnosis was 100%. The correlation between clinical, electrophysiological and MRI findings was poor regarding the severity of the disease. Conclusion: MRI is an excellent diagnostic tool of carpal tunnel syndrome with proven very high sensitivity and capability of detection of the underlying cause of the disease |