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Abstract PET/CT is possibly the superior imaging modality for the initial staging and diagnosis of primary and recurrent head and neck cancers, NSCLC, lymphomas, colorectal, hepatic and pancreatic carcinomas. PET/CT is best at N staging and M staging in these patients, and it is clearly superior to CT and MR in this context. After performing many oncology studies using an integrated PET/CT system, the investigators concluded that combined PET/CT images offer significant advantages, including 1) more accurate localization of foci of uptake, 2) distinction of pathologic from physiologic uptake, and 3) improvement in guiding and evaluating therapy. Many studies confirmed the efficacy of the use of PET/CT radiotherapy treatment planning especially with HNSCC, NSCLC, brain tumors, bulky lymphomas, melanomas. Other tumors are still investigational |