الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 110 |  |  |
| | | from | 110 | | |
Abstract
This retrospective study was conducted in Gastroenterology center, Mansoura University between January 1980 and December 2005 aiming to review the clinicopathological types and treatment of patients with gastrointestinal lymphomas admitted and treated in our center.It included 129 patients with gastro-intestinal lymphoma (104 gastric and 25 intestinal). The mean age for gastric patients was 44.4±12.9 ranging between 16-74,while it was 34±17.46 for intestinal patients ranging between 4-63 .It included 54 females(41.8%)and 75 males (58.2%).All patients were subjected to complete clinical assessment ,laboratory investigations in the form of haematogram with differential leucocytic count, radiological in the form of Chest x ray and/or computed tomography (CT).Abdominal and pelvic ultrasound and/or CT. Bone marrow aspiration and biopsy. Upper GIT endoscopy with biopsy and histopathology. As regard management of gastric cases,39 patients were managed by surgery only,46 patients managed by gastrectomy and chemotherapy Primary gastric lymphoma represented 80.6% of cases of gastrointestinal lymphoma and 16.2% of all gastric malignancies. The main age were 45 year 45 years and 32 years for gastric and intestinal lymphoma respectively. Abdominal pain was the commonest symptom in gastric (88.5%) and intestinal cases (88%). Other symptoms include weight loss, vomiting and bleeding. The most common involved site is the distal third in the stomach and ileum in the small intestine. Ulcer-like lesion were the commonest (65.4%). The operative mortality was 3 cases. Six patients in chemotherapy group died. Another six cases in gastrectomy and chemotherapy group died due to local or systemic nodal recurrence. The five year survival rate for gastric cases was 78% with mean survival 16.7 years. For intestinal cases, the five year survival rate was 53% with mean survival 7.5 years. The longest survival was for the gas¬trectomy group (18.9 years) followed by the group of gastrectomy and postoperative chemotherapy (13 years) and then the group of only chemotherapy (5 years) with a significant difference between the groups (p=0.015).