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العنوان
Assessment of ovarian reserve and color doppler of ovarian stroma after laparoscopic drilling for polycystic ovarian syndrome /
المؤلف
Abd-El Fattah , Hanan Nabil Abd-El Hafez
هيئة الاعداد
باحث / Hanan Nabil Abd-El Hafez Abd-El Fattah
مشرف / Ahmed Ibrahim Foda
مشرف / Abdel Mageed Fathi Mashaley
مشرف / Laila Abdel Hamid El Boghdady
مشرف / Talal Ahmed Youssef Amer
الموضوع
Polycystic ovary syndrome-- Treatment.
تاريخ النشر
2008.
عدد الصفحات
175 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنصورة - كلية الطب - Obstetrics & Gynecology
الفهرس
Only 14 pages are availabe for public view

from 191

from 191

Abstract

Polycystic ovarian syndrome (PCOS) is the most common cause of anovulation ‎among women presenting with infertility. Patients show resistance to clomiphene ‎citrate regimen has long been known to be a target for other modality of management. ‎Laparoscopic ovarian drilling is an option. However this procedure carries a potential ‎risk of inducing premature ovarian failure or diminished ovarian reserve. Objective: ‎Assessment of the ovarian reserve and ovarian stromal hemodynamics before and after ‎laparoscopic ovarian drilling. Methods: pre-operative assessment of basal serum FSH ‎and evaluation of ovarian stromal blood flow using color Doppler flow velocities in ‎seventy-five infertile patients with PCOS comparing results with that early and late ‎post-operative values. Results: There were statistically significant changes in the serum ‎concentrations of early follicular phase FSH after Laparoscopic ovarian drilling (4.4 ± ‎‎1.6 SD mIU/ml (range 2.0 –7.8 mIU/ml) before operation to 6.05 ± 1.68 SD mIU/ml ‎‎(range 3.7 –10.5 mIU/ml) 6–10 weeks after operation. There was also a statistically ‎significant decrease in peak systolic velocity (PSV) and end diastolic velocity (EDV) of ‎ovarian stromal arteries after laparoscopic ovarian drilling (P< 0.001). RI and PI were ‎increased although not significant statistically. Conclusion: Correlation between ‎diminished ovarian stromal blood flow (evidenced by Doppler studies); the coincident ‎diminished ovarian volume, antral follicle count and the increase in serum FSH might ‎give apprehension toward a probable effect of LOD on ovarian reserve. ‎