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Abstract
In this study two groups of patient were included. Non malignant group comprised 60 patients and malignant group comprised 15 patients.
All the patients in both groups were subjected to through history , through clinical examination and then TVS with color flow and pulsed Doppler study and finally from every patient endometrial biopsy was taken which was subjected to:
- Routine histopathological examination .
The results were statistically analyzed and diagnostic accuracy of Doppler ultrasonography in the prediction, diagnosis and prognosis of endometrial carcinoma are calculated .
In this study , 75 patients included presented by abnormal uterine bleeding . Histological examination reveals that 15 cases (20%) proved to be endometrial carcinoma , 46 cases (61%) endometrial hyperplasia , 2 cases (3%) secretary endometrium , 5 cases (7%) proliferative endometrium , 6 cases (8%) atrophic endometrium , and only 1 case (1%) proved to be endometrial polyp . The sonographic finding in cases of endometrial carcinoma were charecterized by an endometrial thickness more than 10 mm . Non of the cases of endometrial carcinoma had endometrial thickness less than 10 mm , while all cases of atrophic endometrium had endometrial thickness less than 5mm . 32.6 % of cases of endometrial hyperplasia had endometrial thickness 5-10 mm , while 67.4 % more than 10 mm . The mean endometrial thickness of non malignant group was 11.23 + 6.04 while in malignant group was 20.67 + 6.58 and this was statistically significant (p<0.001) .In this study , RI was used in analysis of the newly formed blood vessels in the endometrial plate . The angiogensis could be detected in 14 cases out of 15 cases of endometrial carcinoma (93.3%) with the mean RI = 0.34 + 0.05 , while in non malignant group angiogensis could be detected in 13 cases out of 60 (21.7%) with the mean RI = 0.64 + 0.03 . The difference between RI of malignant group and non malignant group was highly significant (p< 0.001)
Recents reports have investigated the role of transvaginal color Doppler ultrasonography as a means of detecteding gynecologic malignancies. Assessment of tumor angiogenesis using color Doppler ultrasound provides useful information for the preoperative prediction regarding stage, depth of myometrial invasion and presence of lymph node metastasis in patients with endometrial carcinoma .
In this study , two groups of patient were included. Non malignant group comprised 60 patients and malignant group comprised 15 patients.
All the patients in both groups were subjected to through history , through clinical examination and then TVS with color flow and pulsed Doppler study and finally from every patient endometrial biopsy was taken which was subjected to:
- Routine histopathological examination .