الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Background: Impaired tissue perfusion can go undetected, despite presence of normal global hemodynamics, causing severe complication. Since the splanchnic area is one of the first to suffer from this derangement, early prevention of splanchnic hypoperfusion can prevent the development of complications.
Methods: Thirty patients scheduled for Whipple operation were randomly classified into 3 groups. group 1 (D0) was the control group. group 2 (D3) received intraoperative infusion of dobutamine at 3 µgm/kilogram.minute. group 3 (D5) received intraoperative infusion of dobutamine at 5 µgm/kilogram.minute. Global hemodynamics and gastric tonometric variables were recorded intraoperatively and during ICU stay at admission, 3, 6, 12 and 24 hours. Patients were followed during hospitalization to detect occurrence of complications.
Results; Postoperative percentage of complications was 70% in the first group, 40% in the second group, 70% in the third group.
Conclusion: Intraoperative dobutamine infusion ameliorated splanchnic hypoperfusion, (reflected on gastric tonometric variables), and decreased the incidence of postoperative complications.