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Abstract Chronic renal failure (CRF) is a functional diagnosis cnaracterized by a progressive and irreversible decline in glomerular filtration rate (GFR) (1) i.e. GFR less than fM/min which correspond* to less than 5’/i of normal nephron f unc tion .De Wardner (2) definec I— a~ a persistent impairment of both glomerular and tubular functions, of gradual onset, and of such severity that the kidneys are no longer able to keep the internal environment normal. |