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العنوان
Mitotic Recombination as a Microbial Assay for Mutagenicity and Carcinogenicity and its Significance to other Assays /
المؤلف
El-Fadly, Gomaah Aly B.
هيئة الاعداد
باحث / جمعه على بهجت الفاضلى
مشرف / حسن جلال
مناقش / عاصم محمد على
مناقش / سالم عبد الكريم
الموضوع
Genetics.
تاريخ النشر
1981.
عدد الصفحات
119 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الهندسة الزراعية وعلوم المحاصيل
تاريخ الإجازة
1/1/1981
مكان الإجازة
جامعة طنطا - كلية الزراعة - Genetics
الفهرس
Only 14 pages are availabe for public view

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from 130

Abstract

this study was designed to determine the eT9iciency of mitotic recombination as a possible assv f o r detecting mutagenicity and carcinogenicity induced by diffezlent chenicals, varying in their effects, in the nomally haploid yeast , Schizosaccharom~cesp ombe and i n the diploid yeast Saccharomyces cerevisiae. The results obtained using Sopombe showed that : .--. 1- The norad segregation (2:2) frequencp which obtained i n the cor,t;rol eqeriment with 5.88 percenk was found to disappear following IriZL’IQG treatments. In contra-st it ms obtained after treatment with different doses of endoxan, although at varying frequenies, however , on the average higher than those obtained in the cmtrol experiment . 2- The dominant u-r honozygosity adr ecessive hanozygosity declioel! steaCily by increasing I!U?XG doses while the? decreased in varying trend coaparecl with the control after treatneat znith endoxan doses . 3- Gene conversion (3D:lR or 1D:JB) did not occur either in the ccnlxvl eqeriment or after treatment with diff e r ent MWJG doses.