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العنوان
A study of platelet factor-4. betathromboglobulin and plasms fibronectin in some chronic liver disease /
المؤلف
Awad-Alla, Olfat Mohamed Hendy.
هيئة الاعداد
باحث / ألفت محمد هندي عوض
مشرف / سامية حسن قنديل
مشرف / طريف حمزة سلام
مشرف / عمرو احمد فتحي
الموضوع
clinical pathology. platelet. platelet Factor4. liver disease.
تاريخ النشر
1996.
عدد الصفحات
190 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء الحيوية (الطبية)
تاريخ الإجازة
1/1/1996
مكان الإجازة
جامعة المنوفية - كلية الطب - الباثولوجيا الاكلينيكية والكيميائية
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study aimed to assess platelet activities in some casesof chronic liver disease by studying some platelet a- granule contents namely PF4, |3-TG and plasma fibronectin, in order to illustrate to what extent alteration of these parameters may influence the performance of platelets with progress of chronic liver disease.This study was performed on 86 cases. 25 normal healthy controls and 61 persons with chronic liver disease selected from the outpatient and inpatient sections of Liver Institute Menoufyia University.The urine, stools and rectal snips examination for schistosoma ova were done. Hepatitis markers for HBV and HCV were done to all cases to diagnose chronic hepatitis. Ultrasonography and liver biopsy were done to the patients.According to the results of liver biopsy, patients were classified into :-Bilharzial fibrosis (18 cases).-Chronic active hepatitis (10 cases).-Compensated cirrhosis (19 cases).Cirrhosis with ascites (14 cases).To all patients and controls the following investigations were lerfbrmed:Routine liver functions test including (serum bilirubin total and Urect, ALT, AST, alkaline phosphatase, total proteins, serum albumin and irothrombin time).