الفهرس | Only 14 pages are availabe for public view |
Abstract Secondary hyperparathyroidism is common in patients with chronic rental failure resulting in the development of variety of clinical complications. Elevated levels of parathyroid hormone occur early in rental insufficiency .The onset of secondary hyperparathyroidism is the result of altered mineral and hormone metabolism, especially deficiency in active vit. D (calcitriol), as the failing kidney decreases production of this hormone Since calcitriol is the primary regular of intestinal calcium uptake, low calcitriol levels can lead to decreased .Serum calcium levels. In addition, low calcitriol levels can affect bone mineralization and alter the paratlyroid gland response to calcium, requiring a higher serum calium level to suppress OTH secretion. As kidney, increasing serum phosphorus These factor lead both to a rapid release of PTH from the parathyroid gland and secondary hyperparathyroidism Cardiovascular risk factor is a significant burden in CRF patients. The influence of PTH on myocardial function in ESRD patients is the design o the present study |