الفهرس 
History of TuberculosisOnly 14 pages are availabe for public view
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Abstract
Tuberculosis (TB) remains one of the major causes of death from a single infectious agent worldwide. (Palomino, 2005). From 8.8 million cases diagnosed in 2002, 3.9 million cases only were sputum +ve according to WHO report 2004. This demonstrates that half of all patients with TB can present with negative sputum smear findings. Despite the initial clinical suspicion of TB, when a patient’s sputum smear results are negative for AFB, the diagnosis of TB may by missed and clinicians must face the dilemma of empirically treating or waiting for up to 8 weeks for the final culture results. (Alka et al., 2001) and the aim of this work is trying to diagnose these patients early as they are also capable of transmitting the infection. So we evaluate the mycobacteria growth indicator tube for detection of mycobacteria in clinical specimens and compare its result with BACTEC 460 and L-J in term of recovery rate, mean time to detection.
This study was done on 150 patients suspected clinically and radiologically to have pulmonary tuberculosis, who were admitted to Al Abbasia Chest Hospital between February 2006 and February 2007. 135 patients were investigated by direct sputum smear stained with Ziehl-Neelsen for three successive days; they were sputum negative for AFB. The bronchoalveolar lavages were obtained from 15 patients who can’t expectorate and also examined by direct smear stain with Z-N, they were negative for AFB. Then we cultured the sputum or BAL on L-J medium, BACTEC 460 TB system and MGIT tube. Of these 150 patients 30 patients were culture positive for MTB.
*All patients subjected to:-
1- Full history taking.
2- Clinical examination.
3- Chest x-ray.
4- Complete blood picture.
5- SGOT, SGPT, Blood Urea, Serum creatinine
6- Sampling for microbiological study which may be sputum or broncho-alveolar lavage to be examined by:-