الفهرس | Only 14 pages are availabe for public view |
Abstract The disturbances associated with chronic renal failure almost always involves the body systems but the respiratory disorders are frequent. The pUlmonaryfunction tests help in diagnosis of these disorders. The aim of this work is to ~tudy the ventilatory abnormalities in patients with chronic renal failure before and after haemodialysis. Twenty patients were studied and selected with absence of overt lung and heart diseases, to all of them full medical history and full clinical examination was done. The following investigations were done: complete urine analysis, full blood picture, blood urea and serum creatinine, serum sodium and potassium, plain X-ray to the chest and heart, abdominal ultrasonography and resting EIOC.G. ventilatory functions studies measuring slow vital capacity (SVC), forced vital capacity (FVC), forced expiratory volume of one second (FEV1), forced expiratory volume of one second/forced vital capacity percent (FEV1/FVC%),forced expiratory flow at 25%-75%and forced expiratory flow at 0.2-1. 2 Ii ters before and after haemodialysis by using vitalograph, peak expiratory flow rate (PEFR)before haemodialysis, half an hour from the starting of haemodialysis and after haemodialysis (four hours) by using Peak Flowmeter. - 99 - The ventilatory function tests measured were compared with the predicted values and with the base line ”before haemodialysis”. The results of this work showed that : * All ventilatory functions before haemodialysis were below normal values as compared with predicted values. * A restrictive pattern was observed in the majority of patients (75%) and obstructive pattern in the rest (25%) before haemodialysis. * There was improvement in all ventilatory functions studied after haemodialysis where SVC and FVC showed statistically non-significant improvement (P < 0.05) while FEV1, FEVl/FVC%, FEF25%_75%’ FEFO•2-1•2 and PEFR showed statistically significant improvement (P < 0.05). * There was statistically non-significant correlation between blood urea level and ventilatory functions (P > 0.05), also there was statistically non significant correlation between body weight and ventilatory functions (P < 0.05) but serum creatinine level showed statistically significant negative correlation after haemodialysis with PEFR (P < 0.05). * The ventilatory functions in patients who lost 2 kgm or more from body weight was greater than who lost less than 2 kgm. * The percent of improvement of the ventilatory functions in patients who received dialysis one year was higher than those who received dialysis more than one year. |