الفهرس 
Laboratory diagnosisOnly 14 pages are availabe for public view
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Abstract
INTRODUCTIOH
Hepatiti virus (A .V) i . a common cause of liver disease and
a major health problem w rldwide (Hsaise! al., 2002/
The prevalence of H ”V infecri II in Egypt is jbe highest rate
allover the world (WHO, 2000). The seropre alence rate accounts for 10-
_0% ill paris of central Africa. Egy I hasa hea y burden of Ii er disea e
mostly due to chronic infection with Hey and attributed to schistosoma
man ni infect! 11 Overall pre alen e f H V antibodie ill the general
population it around 10-15% and i highly prevalent among Egyptian
blood donor (Frank et el; 2000).
urn rou extrahepatic manifestation have been reponed in
a soda ri n vrith heperiris viru (H V infecti n , including renal
eli ea e. neuropathy, lymphoma. and jogren yndrome with or without
mixed cryoglobulinemia (Aguilar Ramirez; 2002). Porphyria cutanea
tarda and diabete have also be 11 linked to H \, Most extrahepati
mauifesratn of chronic Hev infection are immunologi al, and the chronic
infection eems to be nece ary for their development (Mayo. 2003) .
.europathy refer to lilly disease of the nervou sy tem resulting
from localiz d inflammation of the nerves. If ymptom appear in the
body’ extremities, the condition i called ”peripheral neuropathy”. and
mo t H V related ueuropathie are of’thi ort.
It wa generally beliex ed that the hepatiti C viru can damage only
liverand blood. How ver other tudies revealed thai not only did hepatitis
C virus damage the liver and blood, but thai it could also infect neuron
and de troy the entrel nerv 11 y tem, People with hepatiti . who