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Abstract Percutaneou . ablation i considering the be.’ treatment option for patient with early- rage hepatocellular carcinoma wh are nor candidate f< r surgical re e tion Of liv r tran plantation- lm of this hid. : rhisv ark aims to compare the results of some different chemical, thermal and trail arterial ablative modelitie for H rreermenr. Pattents and method: rhi rudy wa conducted on 60 patient with H C The patient were divided into five group: Group 1: included 15 patient treated by alcohol injection, roup 2: includ d 15 patient treated b ethanol-Iipiod I injection, roup 3: included 10 patient treated b a eri acid injection, Group 4: included 10 parienr treated by radiofrequency and Group”: included 10 patient treated by tran arterial chemoemboli arion in Mannheim niversity hospital- German . Re ults: There i no stati tical significant difference between different type of ablative modalities for H trearmenr 11 ed in this mdy regarding focal lesion complete ablation. 10 al or new recurrence (de novo) in focal Ie. ionseirher le than 3 em or from 3 to 5 em, By comparing between f cal le ion ized’” em r le and focal le ion from 3 to : em ill all studied patients treated by any ablati e modality used in thi. study, revealed that there is tali tical significant difference regardingcomplete ablati 11 and local recurrence fter treatment while n tatistical ignificant differen e regarding new recurr I1C (de no 0) le in. One and two year survival rate were 73.,)% and -3.3% in alcohol group, 867% and 60% in alcohol-lipiodol group, 70% and 60% in both radiofrequen y and acetic acid group and 60 and 40% in chemoemboli arion group without statistically significant difference mnong the studied group. onclusiens: Th different studied modalitie for HCC have no stan tical significant difference regarding focal Ie ion completeablation, local or new recurrence, In all patient , compari ou berween Bee focal Ie .ions ized 3 em or les and focal Ie ion from 3 to 5 em reveal d that there is statistical significant difference regarding complete ablation lind local recurrence after ablative therapy. Radiofrequency has better mean survival rate than other u ed modalities of treatment after 24 month f foil IN up bnt there i no tatistical ignificanr difference between .rudi d different H C ablative modalitie regarding one lind two year urvival rate. |