الفهرس | Only 14 pages are availabe for public view |
Abstract 1 - TWenty cases of hepatosplenic bilharaialis with ruptured varices without shock were studied, 19 were males and one was female, with age ranging from 14-53 years. The liver was fibrotic in all cases, normal sized in 6 oases, enlarged in 2 cases and shrun~en in 12 cases. Asoites was present in 15 oases. 2 - Pituitrin was administered to all oases. 3 - All these oases were subjeoted to olinioal examination and investigations inoluding urine, stool analysis and blood examination for blood pioture and blood urea. 4 - The urine flow was measured hourly for 3 hours before and after pituitrin. 5 - The serum and urinary eleotrolytes (Sodium, potassium, Chloride, C aloium and Phosphorus) was measured before; 24 hours, 72 hours and one Week after pi tuitrin. 6 - Marked increase in urinary flow was observed in the first and secozd hours after pituitrin. 7 - Significant increase in urinary sodium excretion was deteoted 2 hours after pituitrin. - 98 - 8 - Insignificant phcsphaturia was observed 2 hours after pituitrin. 9 - As regards other urinary electrolytes (potassium, calcium and chloride) no significant changes were detected. 10- Significant hypocalcaemia was observed 2 hours after pituitrin. 11- As regard other serum electrolytes (sodium, potassium, phosphorus) no significant changes were detected. 12- from this work we can conclude that pituitrin can possibly reduce the portal blood pressure and deccrease the blood loss in patients with hepatosp1- enic bilharziasis and ruptured varices, by its diuretic and natriuretic effects besides its vasoconstrictive action on the splanchinic vessels. |