الفهرس 
Material and methodsOnly 14 pages are availabe for public view
 |  | from | 161 |  |  |
| | | from | 161 | | |
Abstract
SUMMARY
Diabetes Mellitus is a disease process
characterized by an absolute or r-elative insulin
deficiency with concomitant disturbance in the
metabolism of other substrates e.g. protein and fat
and resultant hyper-glycaemia.
Many
described
diabetic
and found
complications have been
to affect almost all body
organs (retinal kidneys, cardiovascular system and
both the peripheral and the central nervous
system) .
One of the most important and wide spread
complications of the diabetic illness is its
microangiopathy which affects the microcirculation
allover the body.
It has been shown that diabetics have
abnormally high blood and plasma viscosities.
All the above mentioned changes would affect
the blood flow through the microcirculation and
may lead to tissue hypoxia.
Since Jordao’s (1857) suggestion of an
association between diabetes mellitus and hearing
1055. many histopathologic. experimentally. and
clinical studies of” the vestibula-cochlear
pathways, both in human and animals with diabetes.
have been made in an effoLt to claL ify the effect
of diabetes mellitus in the inner ear function. The
results of these extensive studies weLe quite
confusing.
Some authors suggested peripheral end oLgan
lesion mor e marked in the cochleaL than in the
vestibular parts of the labyrinth (CoJazzi and
BotneL 1950; costa. 1967).
This pathologic finding was clinically
demonstrated as bilateLsl symmetLical hearing loss
CHegnaL. 1908; MOSOLa at al .• 1975; TayloL and Win.
1978). Increased incidence of MenieL’s disease
among diabetics have been claimed by some other
authors (Kitabchi et al .• 1971; PLoctor. 1981).
Retrocochlear lesion has been suggested by
some histopathologic studies CMakishima and Tanaka,
1971; Naufal and Schuknecht, 1972).
Some clinical studies showed hearing
impairment mostly in the high rrequency range while
others showed low or mid rrequency 105s.
In some reports I an abnormally elevated
stapedial rerlex threshold has been demonstrated in
contrast.to a normal threshold in other reports.
This
questions:
1. Whether there was a correlation between
work aimed to answer two definite
diabetes mellitus and· the cochlear part or
the vestibulo-cochlear nerve.
2. where the maximum insult to the nervous
pathway is likely to occur i.a. where at
the end ~rgan, nervouS pathway or along the
brainstem connections.
Therefore this work studied ~8 stable
diabetics using pure tone (ait’” and bone
conduction), acoustic reflex tht’”BSholds,Tympanometry,
Tone dacay, loudness discomfort level.
1- There was stastically significant correlation
between auditory function and diabetes mellitus
when evaluated by pure tone. There was both high
and low f~equency senso~y neu~al hearing loss
which was bilateral.
2- There was no statistically significant relationship
between hearing loss and the duration of
diabetes mellitus.
3- Stapedius ~eflex thresholds were normal.
~_ Tone decay was negative for all cases and this
denied any retrocochlear lesions.
5- Loudness discomfort level was decreased for all
the cases and this means recruitment. A cochlear
lesion is predicted from this recruitment.
6- Tympanometry results were all within normal and
this denied any affection of the conductive
system of hearing.