الفهرس | Only 14 pages are availabe for public view |
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by activation of the immune system and organ damage secondary to the inflammatory processes which distinguish the disease. The kidney is one of the target organs frequently affected by SLE, however, there is much controversy about the best way to follow up the course of lupus nephritis. Recently serum soluble receptors of various cytokines have been reported to reflect disease activity in many autoimmune diseases including SLE. This study was conducted to determine the value of measuring the levels of sIL-2R in the sera of patients with SLE . The purpose was to detect if the levels of sIL-2R were elevated in SLE patients and if so, whether this correlated with other laboratory data used for eveluation of the disease and its activity and if levels showed any relevance to data collected from the renal biopsy. |