الفهرس 
MicrobiologyOnly 14 pages are availabe for public view
 |  | from | 16 |  |  |
| | | from | 16 | | |
Abstract
Infertility defined as one year of unprotected intercourse without conception, is an important public health problem of considerable magnitude that have a profound effect on the psycho-sexual aspects of the couple’s relationship (Meikle et al., 1994). One of the multifactorial aetiology of infertility is tubal affection following salpingitis. Saplingitis can be caused by a variety of micro organisms of which chlamydia trachomatis represent now one of the most important pathogeneses of salpinigits. According to Dabekausen et al, (1994) the incidence of tubal factor varied from 14% to 38%. This study is to evaluate the importance of chlamydia trachomatis infection as a cause of infertility in our population. The study has been carried out on two groups, the first group (study group) consists of eighty infertile patients, and the second group (control group) consists of twenty healthy normal pregnant women. While both groups were subjected to serological diagnosis of chlamydia trachomatis infection, the study group was subjected to HSG and laparoscopy. The IgA antichlamydial antibodies were detected in 44 infertile patients (55%) and in 2 women (10%) of the control group, while the IgG antichlamydial antibodies were detected in 36 infertile patients (45%) and in one women (5%) of the control group. These results are statistically significant and can be point to the important role of chlamydial infection among the infertile women. Among the cases with high positive antichlamydial antibodies abnormal tubal factor was almost always seen in HSG. Laparoscopic abnormalities were detected in 29 patients (80.6%) with positive (+ve) and in 7 patients (87.5%) with high positive (++ve) 19A antichlamydial antibodies. Also, it was detected in (100%) of patients with high positive (++ve) IgG antibodies. We conclude from the results obtained in our study that the serological diagnosis of chlamydial infection by the detection of IgA and IgG antibodies is an important step in the infertility work up. Also we suggest the possible initial evaluation of tubo-peritoneal factor in cases with positive (+ve) and high positive (++ve) IgA antibodies and high positive (++ve) IgG antibodies by laparoscopy with facilities for operative procedures in those patients as their laparoscopic evaluation reveal highly significant inflammatory tubo peritoneal abnormalities.