الفهرس 
Review of literatureOnly 14 pages are availabe for public view
 |  | from | 16 |  |  |
| | | from | 16 | | |
Abstract
The leukocyte adherence inhibition (LAI) test since its early introduction (and up till now) was applied to detect cell mediated immunoreactivity related to various types of human diseases specially cancer. Our previous studies of human urinary bladder squamous cell carcinoma has been conducted in this issue and expanded to other tumor types as well as shistosomases.at early stage of the disease to get of fetal calf serum (ECS) was avoided adherence inhibition of leukocytes. al blood leukocytes (PaL) from either carcinoma patients in serum free medium, percen was estimated and considered as control level of The toxicity of the tumor extracts (SqCC/UB, TrCC/U8, AdnC/UB and SqCC/CX) and other extracts (NorE/UB/82 and Shaem/SEA/83) was exa mined. The nontoxic concentrations (at which nonspecific reduction of cell adherence was not observed) were determined and found to be of 250 ug/ml for all extracts but 25 ug/ml for Shaem/SEA/83 extract.Although tumor extracts were prepared by one and the same method, different tumor antigen preparations varied vastly in their ability to give specific adherence inhibition. All preparations consistently gave a high tumor specific LAI (20% decreased adherence or more). Only the SqCC/UB2/82 failed to express such level of adherence reduction. Use of this extradt was avoided. Cancer patients were chosen the highest reactivity and usage because it causes nonspecific Following incubation of peripher control subjects or tage adherent cells adherence.