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Abstract In Egypt, Niclosamide ethanolamine (Bayluscide®) is used on a large scale as an excellent molluscicide to control water snails. The product is currently used from 1968 and contaminate the Egyptian water ways, three times a year ”Spring, Summer, Autumn” (Kenneth, 1987). Continuous use of these substances usually have dangerous effects on the aquatic animals especially fish (Foster, 1962; Weebe, 1962 and Hulbert, 1975). This pollution result in adverse effects on human being through consumption of contaminated water and/or fish (Hank et al., 1983; Gluth and Hank, 1984 & 1985 and Abo Hegab et al, 1989). As an unintended effect, Bayluscide is toxic to all fish species at 0.5 mg/L and to zooplanktons and aquatic vegetations at high concentrations (WHO, 1988). Moreover, pesticide exposure of human beings and animals during pregnancy carries with it a significant risk to feti (Persaud, 1979; Davis, 1991). The present study was undertaken to perform environmental toxicity; teratogenicity, pre- and post-natal toxicity as well as reproductive toxicity (male and female fertility) studies including evaluation of haematological parameters, biochemical analysis, thyroid function, residual hazard and histopathological findings due to the use of Nicolsamide as moulluscide. |