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Abstract Congenital abnormalities are any structural, functional or biochemical abnormalities present at birth. It has been recognized in recent years as an important source of human morbidity, mortality and disability. The aim of this work was to estimate the prevalence of some clinically apparent congenital abnormalities among infants attending health offices in Alexandria, and to measure the association between it and the possible predisposing factors. This aim was accomplished by studying cross sectional sample of 803 infant (0-12 months old) attending health offices for immunization. Six health offices were randomly selected, one health office from each district. Each was visited for one month in the days of vaccinations for the target age groups, one every third infant was invited to participate in this study and was subjected to interview questionnaire and clinical examination. Results of this study can be summarized in the following: A. Main sample characteristic: 1. Male to female ratio was 1.1:1 and the largest group of infants in the study sample was aged 0-3 months (39.2). The first and second birth orders had the highest frequencies (39.5-32.9). |