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Abstract
A
lthough mechanical ventilation is a life-saving intervention for pediatric patients suffering from acute respiratory failure, it is associated with numerous grave complications and should be discontinued at the earliest possible time. However, both delayed and premature weaning may be harmful, so the need for accurate prediction of weaning outcome is important.
The pathophysiology underlying weaning failure is complex and the cardiac function and, more importantly, volume status may play a role in this setting.
The present study prospectively studied 20 mechanically ventilated infants and children who are mechanically ventilated for more than 24 hours and were considered ready to undergo a one hour spontaneous breathing trial (SBT).