الفهرس | Only 14 pages are availabe for public view |
Abstract Birth asphyxia remains in important cause of perinatal mortality in developing countries. Much progress has been made toward understanding the mechanisms contributing to ongoing brain injury following hypoxia ischemia. Cytokine-mediated inflammatory reactions are important in the cascade leading to hypoxic ischemic brain injury following birth asphyxia In this study, we aimed: to assess whether or not CSF and serum IL-6 levels are affected in perinatal asphyxia, to correlate the CSF IL-6 level to the clinical severity of hypoxic ischemic encephalopathy and to find any correlation between CSF and serum IL-6 in perinataly asphyxiated infants. The study cases were 34 asphyxiated newborns, they were subjected to the following: 1- Apgar scoring. 2- ABG analysis. 3- Renal function. 4- Blood glucose leveling. 5- CBC. 6- Serum and CSF IL-6 level. 7- Imaging study. |