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Abstract Trichinosis constitutes one of the most important zoonotic problems in the world especially in temperate zones, but rare in Islamic countries. The parasite, Trichinella spiralis, can spread easily among pork- eaters through predation and consumption of carrion. Its occurrence in man depends mainly on the dietary habits of the population with regard to the consumption of raw, inadequately cooked pork. The objectives of this work were mainly directed to study the prevalence of Trichinella spiralis, the ecological factors influencing the distribution of Trichinella spiralis among rodents and the effects of Trichinella spiralis infection on some lysosomal enzymes activity and specific activity. In this work, the total number of collected rodents sample from the six districts of Alexandria (El-Montaza, East, Middle, El-Gomrok, West, El-Amryia Districts) was 1025 rodents in the period from August 1995 to June 1996 from and around the abattoir, schools, houses, storages and tanneries. Classification, weighing and collection of the wisdrawel blood, muscles, diaphragm, thigh, tongue, liver and spleen were done to be used for parasitological and biochemical investigation. The total number of rodents’ sample divided according to its species, weight, age and gender to find the correlation between the infection and these variables. The results were recorded in special sheets and tabulated and analysed using Epi-Info software package. The statistical measures were used arithmetic mean, standard deviation, percentage, X2 test, fisher’s exact test, T test, ANOVA test, correlation coefficient, odds ratio (OR), X2MHS Chi-Squares Mantel-Haenszel and the 0.05, 0.01& 0.001 levels were used as cutoff value for statistical significant. It was observed that Rattus norvegicus species represented 41.9 of the total sample, while the other two species, Rattus rattus species and Mus musculus species represented 37.2 and 20.9 respectively. |