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Abstract The continuing search for a simple , non-invasive , but reliable method for detecting ovulation , is not only useful in the management of infertile patients » but also would allow more precise utilisation of mechanical or chemical contraceptives , and might well enhance the efficiency and acceptability of timed periodic abstinence as a technique for fertility regulation . Ovulation can be detected by different parameters such as examination of cervical mucus , baeal body temperature chart, serial vaginal smears and measurement of 21* hours urinary pregnanediol , These require careful monitoring of the patient over a long period of time . Although examination o f a premenstrual endometrial biopsy ie a simple and reliable for detecting ovulation , it is annoying to the patient and carries the risk of interrupting an early pregnancy . Now , the specificity and sensitivity of radioimmunoassays make it possible to measure hormone levels in various body fluids , Accordingly , plasma progesterone measurement is a good method for ovulation detection , although it involves a venepuncture , So, the determinatio |