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Abstract Helicobacter pylori is a microerophilic gram negative organism. It is a cause of peptic ulcer disease and known to be associated with other gastrointestinal disorders. Recently, it is assumed that H. pylori organism is associated with a wide variety of exfcra-gastrointestinal diseases e.g. coronary heart diseases, rheumatoid arthritis, urticaria, and other diseases. Bronchiectasis is a debilitating disease and the affected patients suffer from distressing regular sputum production, hemoptysis, and recurrent infective exacerbations. Recently high seroprevalence of H. pylori with bronchiectasis has been detected. The aim of this work was to investigate the role of H, pylori in bronchiectasis. This study was conducted on 20 bronchiectatic patients ( 12 males and 8 females ) with a mean age 53.75 ± 12.48 years. Ten apparently healthy individuals serving as controls ( 7 males and 3 females ) with a mean age 48.1 ± 13.39 years. The bronchiectatic patients were subjected to complete history taking and physical eKaminatiou, routine laboratory investigations, sputum examination ( culture, Z.N. staining and urease test), plain chest X-ray, CT scan of me chest, upper gastrointestinal |