Search In this Thesis
   Search In this Thesis  
العنوان
The effect of captopril and nifedipine on monoamine oxidase enzyme activity of the rabbit’s brain and liver =
الناشر
Alex uni F.O.Medicine,
المؤلف
Mady,Naglaa Ibrahim Mahmoud .
هيئة الاعداد
مشرف / محمد الدخاخنى
مشرف / محمد ثروت غنيم
مشرف / عواطف هلال
باحث / نجلاء ابراهيم محمود
الموضوع
Pharmacology .
تاريخ النشر
1986 .
عدد الصفحات
105p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/1986
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Pharmacology
الفهرس
Only 14 pages are availabe for public view

from 16

from 16

Abstract

It is well known that many dru^s can alter the monoainijie oxidase easyme activity in the brain and peripheral tissues, thua producing oia^y Important pharmacological effects. Some dru^s can decrease while others can increase the 1IAO enzyme activity both in-vivo and in-vitro .
In this work, an attempt was made to study the effect of two antihy^ertensive drugs namely; captopril uad nifedi-pine oti the IMO enzyme activity of the rabbit^ liver and
brain -
This work was carried out experimentally on ninety six adult male Oryotalagus Cuntculus (balady) rabbits, weighing
from 1 to 1.5 k& body weight .
~
The drugs used were :
1- Captopril (Capoten) tablets each one contains 25 mg. It ffus flu^peaded in 0.5?& G1”11 Acacia mucilage .
2- lilfedipine (Adalat): The pure powder was used In this worjc and it was dissolved In polyethylene glycol (200),
In this work both the in-vivo and io-vitro effects of each of the two dru^s on the uJAQ enzyme activity of the liver and brain were studied