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Abstract
Human umbilical cord blood has proven to be a feasible alternative source
of haematopoietic stem cells for pediatric and some adult patients with major
haematologic disorders.This has promoted the establishment of cord blood banks for
use in unrelated transplants worldwide. Separation, cryopreservation and thawing
techniques have been established and do not seem to affect the viability and
progenitor cell recovery or the feasibility of CD34+ selection and ex vivo expansion.
Conclusion:
Human umbilical cord blood is an attractive source of haematopoietic stem
cells, and has proven to be useful in the treatment of many haematological and nonhaematological
disorders.