الفهرس Only 14 pages are availabe for public view
 |  | from | 255 |  |  |
| | | from | 255 | | |
Abstract
Diabetes mellitus is a complex metabolic disorder with oxidant/antioxidant defense disturbances with increased oxidative stress (1) which may contribute to accelerated atherosclerosis (2).
Oxidative stress is imbalance between free radicles and reactive oxygen and nitrogen species and antioxidant in favor of free radicles (3). It is one of the metabolic events associated with diabetes and its complications (4).
Advanced oxidative protein products (AOPP) seems to be considered a useful marker to estimate degree of oxidative protein damage (1).
AOPP were increased in both types of diabetes mellitus with higher serum levels in patients with type 2 diabetes mellitus (6). They were significantly higher in diabetic patients with complications than diabetic patients without complications. These results may point to oxidatively modified proteins as a differential factor possibly related to pathogenesis of diabetic complications (7).